A Biologist's Guide to Analysis of DNA Microarray ...

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Title: A Biologist's Guide to Analysis of DNA Microarray Data
Description:
Pages: 144

Microarrays are low-density arrays of DNA molecules that permit many hybridization experiments

to be performed in parallel. A Biologists Guide to Analysis of DNA Microarray Data is the

first authoritative text to focus on analysis (as opposed to technology) in diverse biological

and medical applications of microarrays.
Written for biologists without special training in data analysis and statistics, the Guide

takes over where the image analysis software that accompanies DNA array equipment typically

leaves offwith a file of signal intensities and fold changes compared to a control. The broad

spectrum of established analysis approaches is covered, including cluster analysis, function

prediction, and principal component analysis. A thorough, critical review of software programs

is presented, and criteria for selecting programs are discussed. Each chapter contains a

Further Reading section categorized by topic as well as a summary, and highlights numerous real

examples to illustrate the key concepts. Chapter topics include:
* Basic data analysis
* Visualization by reduction of dimensionality
* Cluster analysis of expression data
* Molecular classifiers
* Genotyping chips
* Software issues and data formats
A Biologists Guide to Analysis of DNA Microarray Data meets the needs of research

professionals, students, and trainees alike for a compact yet thorough guide to analyzing

microarray data.

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