A Biologist's Guide to Analysis of DNA Microarray ...
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Description
Title: A Biologist's Guide to Analysis of DNA Microarray Data
Description:
Pages: 144
Microarrays are low-density arrays of DNA molecules that permit many hybridization experiments
to be performed in parallel. A Biologists Guide to Analysis of DNA Microarray Data is the
first authoritative text to focus on analysis (as opposed to technology) in diverse biological
and medical applications of microarrays.
Written for biologists without special training in data analysis and statistics, the Guide
takes over where the image analysis software that accompanies DNA array equipment typically
leaves offwith a file of signal intensities and fold changes compared to a control. The broad
spectrum of established analysis approaches is covered, including cluster analysis, function
prediction, and principal component analysis. A thorough, critical review of software programs
is presented, and criteria for selecting programs are discussed. Each chapter contains a
Further Reading section categorized by topic as well as a summary, and highlights numerous real
examples to illustrate the key concepts. Chapter topics include:
* Basic data analysis
* Visualization by reduction of dimensionality
* Cluster analysis of expression data
* Molecular classifiers
* Genotyping chips
* Software issues and data formats
A Biologists Guide to Analysis of DNA Microarray Data meets the needs of research
professionals, students, and trainees alike for a compact yet thorough guide to analyzing
microarray data.
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