Anticancer Agents from Natural Products

Description

Anticancer Agents from Natural Products

Title: Anticancer Agents from Natural Products 2005-06
Author: Gordon M. Cragg (Editor), David J. Newman (Editor), David G. Kingston (Editor), David G.I. Kingston (Editor)
Publisher: CRC
Publication Date: 2005-06-13
Number Of Pages: 600

Anticancer Agents from Natural Products
By: Gordon M. Cragg(Editor) David G. I. Kingston(Editor) David J. Newman(Editor)
ISBN: 0849318637
Publisher: CRC - 2005-06-13
Hardcover | 600 Pages | List Price: $179.95 (USD) | Sales Rank: 291456

Anticancer Agents from Natural Products
By: Gordon M. Cragg(Editor) David G. I. Kingston(Editor) David J. Newman(Editor)
ISBN: 0849318637
Publisher: CRC - 2005-06-13
Hardcover | 600 Pages | List Price: $179.95 (USD) | Sales Rank: 291456

Table of Contents

Ch. 1 Introduction 1
Ch. 2 Champtothecin and its analogs 5
Ch. 3 The discovery and development of the combretastatins 23
Ch. 4 Homoharringtonine and related compounds 47
Ch. 5 Podophyllotoxins and analogs 71
Ch. 6 Taxol and its analogs 89
Ch. 7 The vinca alkaloids 123
Ch. 8 The bryostatins 137
Ch. 9 The isolation, characterization, and development of a novel class of potent antimitotic macrocyclic depsipeptides : the cryptophycins 151
Ch. 10 Chemistry and biology of the discodermolides, potent mitotic spindle poisons 171
Ch. 11 The dolastatins : novel antitumor agents from Dolabella auricularia 191
Ch. 12 Ecteinascidin 743 (ET-743; Yondelis), aplidin, and kahalaide F 215
Ch. 13 Discovery of E7389, a fully synthetic macrocyclic ketone analog of halichondrin B 241
Ch. 14 HTI-286, a synthetic analog of the antimitotic natural product hemiasterlin 267
Ch. 15 The actinomycins 281
Ch. 16 Anthracyclines 299
Ch. 17 Ansamitocins (maytansinoids) 321
Ch. 18 Benzoquinone ansamycins 339
Ch. 19 Bleomycin group antitumor agents 357
Ch. 20 Biochemical and biological evaluation of (+)-CC-1065 analogs and conjugates with polyamides 383
Ch. 21 Epothilone, a myxobacterial metabolite with promising antitumor activity 413
Ch. 22 Enediynes 451
Ch. 23 The mitomycins 475
Ch. 24 Staurosporines and structurally related indolocarbazoles as antitumor agents 499
Ch. 25 Combinatorial biosynthesis of anticancer natural products 519
Ch. 26 Developments and future trends in anticancer natural products drug discovery 553

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