Assessing the Human Health Risks of Trichloroethylene: Key Scientific Issues

Description

Table of Contents :

Front Matter i-xvi
Summary 1-11

1 Introduction 12-19
2 Methodological Consideration in Evaluating Epidemiologic Literature on Cancer and Exposure to Trichloroethylene 20-46
3 Kidney Toxicity and Cancer 47-111
4 Liver Toxicity and Cancer 112-148
5 Reproductive and Developmental Toxicity 149-172
6 Neurotoxicity 173-188
7 Respiratory Tract Toxicity and Cancer 189-199
8 Immunotoxicity 200-205
9 Special Population and Susceptibility 206-223
10 Mixtures 224-239
11 Pharmacokinetic Modeling 240-254
12 Issues in the Assessment of Dose Response 255-265

References 266-327

Appendix A Biographic Information on the Committee on Human Health Risks of Trichloroethylene 328-332
Appendix B Participants at Public Sessions 333-334
Appendix C Trichloroethylene Metabolism 335-347
Appendix D Exposure Anaylsis of Selected Studies 348-356
Appendix E Peroxisome Proliferators and Liver Cancer 357-362

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