Biochemical Pharmacology Lecture Notes, 3rd edition, 2007

What is ¡®biochemical pharmacology¡¯?
• A fancy way of saying ¡®pharmacology¡¯, and of hiding the fact that we are sneaking a subject of medical interest into the UW biochemistry curriculum.
• An indication that we are not going to discuss prescriptions for your grandmother¡¯s aching knee; we will focus on the scientific side of things but not on whether to take the small blue pill before or after the meal.
What is it not?
• A claim that we accurately understand the mechanism of action of each practically useful drug in biochemical terms.
• A claim that enzyme mechanisms and receptor structures, or even cell biology suffice as a basis to understand drug action in the human body (how do you measure blood pressure on a cell culture?). In fact,we are going to spend some time with physiological phenomena such as cell exitation and synaptic transmission that are targeted by many practically important drugs.

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