Camptothecins in Cancer Therapy (Cancer Drug Discovery and Development)

Description

Camptothecins in Cancer Therapy (Cancer Drug Discovery and Development)

Publisher: Humana Press
Number Of Pages: 474
Publication Date: 2005-02-01
Sales Rank: 354687
ISBN / ASIN: 1588290271
EAN: 9781588290274
Binding: Hardcover
Manufacturer: Humana Press
Studio: Humana Press

Book Description:

A critical review our current understanding of camptothecins, their shortcomings, and of the possibilities for improving their clinical performance. The authors discuss new camptothecin analog development, drug delivery issues for optimizing their anticancer activity, and their potential use in a variety of different cancers. Additional chapters describe what is known freeduan.com about the biochemistry, the pharmacology, and the chemistry of the camptothecins, including the mechanism of topoisomerase and how camptothecins poison this enzyme, the use of animal models in defining the anticancer potential of camptothecins, and the question of camptothecin resistance.

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