Chemokine Biology - Basic Research and Clinical Ap...

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Title: Chemokine Biology - Basic Research and Clinical Application: Vol. 1
Description:
Immunobiology of Chemokines (Progress in Inflammation Research)
Pages: 208

Chemokines play an important role in recruiting inflammatory cells into tissues in response to

infection and inflammation. They also play an important role in coordinating the movement of T-cells,

B-cells and dentritic cells, necessary to generate an immune response (response to injury, allergens,

antigens, invading microorganisms). They selectively attract leukocytes to inflammatory foci, inducing

both cell migration and activation. They are involved in various diseases, like atherosclerosis, lung

and skin inflammation, multiple sclerosis, or HIV.Volume 1 of this two-volume set discusses the

immunobiology of chemokines. It is divided into two parts: a) cellular targets in innate and adaptive

immunity, and effector cell traffic-unrelated functions. Together with volume 2, which discusses the

pathophysiology of chemokines, both volumes give a comprehensive overview of chemokine biology.

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