Clinical Applications of Capillary Electrophoresis

Description

Title: Clinical Applications of Capillary Electrophoresis
Description:
(Methods in Molecular Medicine)
Pages: 212


Stephen M. Palfrey brings together for first time a collection of detailed capillary electrophoresis

protocols designed exclusively for clinical applications. Written by the leading scientists who have

often perfected these methods in their own laboratories, the protocols furnish new and more powerful

assays for many routine serum and blood tests now regularly performed in clinical laboratories,

including serum and urine proteins, hemoglobin separation, and the detection of CSF proteins,

lipoproteins, myoglobin, cryoglobulins, and cathepsin D. The protocols offered for DNA analysis

include double-stranded DNA analysis, the prenatal diagnosis of Downs syndrome, Rh D/d genotyping,

the identification of mutated p53 oncogene, and the detection of microstaellite instability in

cancers. Many of the methods can be automated to replace more labor intensive and costly tests that

are currently used in most clinical laboratories. Clinical Applications of
Capillary Electrophoresis demonstrates clearly the simplicity, versatility, and power of CE over

conventional methods.

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