DNA Repair Protocols, Eukaryotic Systems

Description

Title: DNA Repair Protocols, Eukaryotic Systems
Description:
Pages: 641

From the Publisher
This groundbreaking manual provides step-by-step methods covering all aspects of the cellular

response to DNA damage, including nucleotide and base excision repair, DNA strand break repair,

mismatch repair and tolerance mechanisms. The techniques are based on eukaryotic model systems

in widespread use that have made, or have the potential to make, important contributions to our

understanding of cellular responses to DNA damage in relation to mutagenesis, carcinogenesis,

and the cell cycle. The majority of the chapters are devoted to mammalian cells, which reflects

the allocation of resources in the DNA repair field. Non-mammalian model systems are also

covered, and specifically yeasts, drosophila, Xenopus and plants, the latter of which are of

vital interest given the problem of ozone depletion and consequent loss of UV protection. The

practical methods offered in this book will encourage the transfer of methodologies between

model systems and stimulate the reader's development of new approaches in the study of DNA

damage and repair.

Links

http://linkgrabber.blogspot.com/2006/11/dna-repair-protocols-eukaryotic.html




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