Death Receptors in Cancer Therapy (Cancer Drug Discovery and Development)

Description

Death Receptors in Cancer Therapy (Cancer Drug Discovery and Development)

Publisher: Humana Press
Number Of Pages: 384
Publication Date: 2004-12-03
Sales Rank: 2146925
ISBN / ASIN: 1588291723
EAN: 9781588291721
Binding: Hardcover
Manufacturer: Humana Press
Studio: Humana Press

Book Description:

An in depth review of our latest understanding of the molecular events that regulate cell death and those molecules that provide targets for developing agonists or antagonists to modulate death signaling for therapeutic purposes. The authors focus on the extrinsic system of death receptors, their regulation and function, and their abnormalities in cancer. Topics of read.freeduan.com particular interest include resistance to apoptosis, TRAIL signaling, death receptors in embryonic development, mechanisms of caspase activation, and death receptor mutations in cancer. Additional chapters address death signaling in melanoma, synthetic retinoids and death receptors, the role of p53 in death receptor regulation, immune suppression of cancer, and combination therapy with death ligands.

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