Development of the Nervous System, Second Edition by Dan H. Sanes, Thomas A. Reh, and William A. Harris

Description

The human brain—perhaps the most complex object in our universe—is composed of billions of cells and trillions of connections. It is truly a wonder of enormous proportions. Although we are far from a thorough understanding of our brains, study of the way that the cellular constituents of the nervous system, the neurons and glia, work to produce sensations, behaviors, and higher order mental processes has been a most productive area of science. However, more and more, neuroscientists are realizing that we are studying a moving target-growth and that changes are integral to brain function, forming the very basis for learning, perception, and performance. To comprehend brain function, then, we must understand how the circuits arise and the ways in which they are modified during maturation. Santiago Ramón y Cajal, one of the founders of modern neuroscience, was able to make his remarkable progress in studies of the cellular makeup of the nervous system in large part because of his work with the embryonic brain, choosing to study “the young wood, in the nursery stage . . . rather than the . . . impenetrable . . . full grown forest.”

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