Fluoropyrimidines in Cancer Therapy (Cancer Drug Discovery and Development)

Description

Leading cancer researchers update and review the mechanisms of action and the therapeutic selectivity and efficacy of 5-FU with and without leucovorin and its prodrugs in the treatment of colorectal cancer. Among the combination agents considered are UFT/LV, 5-FU/EU, capecitabine (Xeloda), S-1, and a variety of thymidylate synthase inhibitors. The authors discuss the potential advantages and disadvantages of these varied drugs and their mode of administration. Based on historical results with these agents when used alone, they also present a rationale for their results when used in combination with other agents.




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1. Ebooks list page : 1473
2. Fluoropyrimidines in Cancer Therapy (Cancer Drug Discovery and Development)
3. Combination Cancer Therapy: Modulators and Potentiators (Cancer Drug Discovery and Development)
4. EGFR Signaling Networks in Cancer Therapy (Cancer Drug Discovery and Development)
5. Combination Cancer Therapy Modulators and Potentiators (Cancer Drug Discovery and Development)
6. Matrix Metalloproteinase Inhibitors in Cancer Therapy (Cancer Drug Discovery and Development)
7. Matrix Metalloproteinase Inhibitors in Cancer Therapy (Cancer Drug Discovery and Development)
8. Farnesyltransferase Inhibitors in Cancer Therapy (Cancer Drug Discovery and Development)
9. Camptothecins in Cancer Therapy (Cancer Drug Discovery and Development) by: Val R. Adams
10. Death Receptors in Cancer Therapy (Cancer Drug Discovery and Development)
11. Proteasome Inhibitors in Cancer Therapy (Cancer Drug Discovery and Development)
12. Antiangiogenic Agents in Cancer Therapy (Cancer Drug Discovery and Development)
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14. Antiangiogenic Agents in Cancer Therapy (Cancer Drug Discovery and Development)
15. Chemoradiation in Cancer Therapy (Cancer Drug Discovery and Development)
16. DNA Repair in Cancer Therapy (Cancer Drug Discovery and Development)