Inhibitors of Cyclin-dependent Kinases as Anti-tumor Agents (Crc Enzyme Inhibitors)

Description

Inhibitors of Cyclin-dependent Kinases as Anti-tumor Agents (Crc Enzyme Inhibitors)

Publisher: CRC
Number Of Pages: 448
Publication Date: 2006-10-25
Sales Rank: 1232962
ISBN / ASIN: 0849337747
EAN: 9780849337741
Binding: Hardcover
Manufacturer: CRC
Studio: CRC
Average Rating: 5
Total Reviews: 1

Book Description:

One of the few books to cover all aspects of cyclin-dependent kinases (CDKs), this volume provides an overview of CDKs as molecular and functional entities, their involvement in different disease processes, and their potential for pharmacological modulation. The first two sections discuss the integration of cell cycle control pathways, opportunities for targeting, targets of inhibitors, and the evaluation of CDK inhibitors. The third section examines the design, development, and chemistry of small molecule CDK inhibitors. The final section assesses the current status of CDK inhibitors in clinical trials, the therapeutic deployment challenges of small molecule inhibitors, and the future development of CDK inhibitors as anticancer agents.

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