Ligand Design for G Protein-coupled Receptors

Description

G protein-coupled receptors (GPCRs) are one of the most important target classes in pharmacology and are the target of many blockbuster drugs. Yet only with the recent elucidation of the rhodopsin structure have these receptors become amenable to a rational drug design.

Based on recent examples from academia and the pharmaceutical industry, this book demonstrates how to apply the whole range of bioinformatics, chemoinformatics and molecular modeling tools to the rational design of novel drugs targeting GPCRs.

Essential reading for medicinal chemists and drug designers working with this largest class of drug targets in the human genome.

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1. Ebooks list page : 2584
2. G Protein-Coupled Receptors: Structure, Function, and Ligand Screening
3. G Protein-Coupled Receptors: Structure, Function, and Ligand Screening
4. The G Protein-Coupled Receptors Handbook
5. Orphan G Protein-Coupled Receptors and Novel Neuropeptides
6. G Protein-Coupled Receptors in Drug Discovery
7. G Protein-Coupled Receptors in Drug Discovery
8. G Protein-Coupled Receptors in Drug Discovery
9. Orphan G Protein-Coupled Receptors and Novel Neuropeptides (2008)
10. Methods in Molecular Biology, vol.552 - G Protein-Coupled Receptors in Drug Discovery
11. Understanding G Protein-coupled Receptors and their Role in the CNS (The Molecular and Cellular Neurobiology Series)
12. G Protein-Coupled Receptors as Drug Targets: Analysis of Activation and Constitutive Activity
13. G Protein-coupled Receptors: Molecular Pharmacology By Georges Vauquelin, Bengt von Mentzer
14. Protein-Ligand Interactions: From Molecular Recognition to Drug Design
15. 3D QSAR in Drug Design: Ligand-Protein Interactions and Molecular Similarity
16. The Serotonin Receptors: From Molecular Pharmacology to Human Therapeutics (The Receptors)