Mitochondrial DNA: Methods and Protocols
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Title: Mitochondrial DNA: Methods and Protocols
Description:
Pages: 432
Internationally recognized authorities describe in great detail the methods they have perfected
to analyze mtDNA and the proteins involved in its maintenance. The analytical techniques cover
the purification of mtDNA from a variety of sources and the analysis of DNA for both deletions,
point mutations, and damage, for replication intermediates, and for following the fate of mtDNA
outside of the mitochondria. Additional analytical methods are presented for analyzing the
proteins and enzymes that maintain mtDNA. Comprehensive and timely, Mitochondrial DNA: Methods
and Protocols offers both basic and clinical researchers proven cutting-edge methods for
analyzing mtDNA and illuminating the role it plays in the aging process, apoptosis, and
possibly some cancers.
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