Nucleic Acids in Innate Immunity (2008)

Description

Description: Until recently, innate immunity was regarded as a relatively nonspecific system designed to engulf and destroy pathogens. However, new studies show that the innate immune system is highly developed in its ability to discriminate between self and foreign entities. Understanding this mechanism can lead to therapeutic strategies based on manipulation of this previously unexploited branch of the immune system.
Drawing on the research of leading experts, Nucleic Acids in Innate Immunity provides insight in this new area of immunology. The book begins by explaining the roles of nucleic acids in immunity, describing the mechanism of discrimination based on pattern-recognition receptors (PRRs), including Toll-like receptors (TLRs), Nod-like receptors (NLR), and RIG-I-like receptors (RLR). Chapters discuss how these PRRs recognize and respond to pathogen-associated molecular patterns (PAMPs) by activating specific signaling pathways.
The second section focuses on the therapeutic applicationsof immunomodulatory DNA by manipulating released pathogenic nucleic acids as immune system stimulants. The book introduces novel therapeutics developed to prevent or treat infectious diseases, allergic disorders, and cancer, as well as clearing unnecessary or abnormal host molecules.
The final section addresses how the immune system discriminates self and non-self RNA. Recent findings that host (self) nucleic acids are not inert in the immune system beg the question of exactly what elements within DNA or RNA are recognized by the innate immune system. Contributions review recent advances to understand innate immune recognition of nucleic acids and describe the resulting immune modulation.
Providing a comprehensive review of nucleic acid recognition and regulation by the innate immune system, this seminal work reveals new directions for future research in immune modulation.




Check all my medical and biology related posts at MyAvaxBlog



Download from
http://hotuploading.com/index.php?page=main&id=662ce438&name=NAIII2008_www.bioXplorer.com.rar

Disclaimer:
Contents of this page are indexed from the Internet. All actions are under your responsability. Email us to report illegal contents or external links and we'll remove them immediately.

Please check the description for download links if any or do a search to find alternative books.

Can't Download?
Please search mirrors if you can't find download links for "Nucleic Acids in Innate Immunity (2008)" in "Description" and someone else may update the links. Check the comments when back to find any updates.

Search Mirrors
Maybe some mirror pages will be helpful, search this book at top of this page or click here to find more info.

1. Ebooks list page : 1708
2. Innate Immunity of Plants, Animals and Humans (Nucleic Acids and Molecular Biology)
3. Trends in Innate Immunity (2008)
4. Radiation Induced Molecular Phenomena in Nucleic Acids: A Comprehensive Theoretical and Experimental Analysis (2008)
5. Molecular Aspects of Innate and Adaptive Immunity
6. Innate Immunity (Methods in Molecular Biology)
7. Mechanisms of Lymphocyte Activation and Immune Regulation X: Innate Immunity
8. Mechanisms of Lymphocyte Activation and Immune Regulation X: Innate Immunity (2007)
9. Mechanisms of Lymphocyte Activation and Immune Regulation X: Innate Immunity (2007)
10. Current Topics in Innate Immunity (Advances in Experimental Medicine and Biology)
11. [share_ebook] Innate and Adaptive Immunity in the Tumor Microenvironment
12. Modulation of Host Gene Expression and Innate Immunity by Viruses by Peter Palese
13. Crossroads between Innate and Adaptive Immunity by: Peter D. Katsikis, Bali Pulendran, Steven P. Schoenberger
14. Advances in Experimental Medicine and Biology, vol.598 - Current Topics in Innate Immunity (2007) - RE-UPLOAD!
15. Quadruplex Nucleic Acids
16. Synthetic Nucleic Acids