Optimization in Drug Discovery (Methods in Pharmacology and Toxicology)

Description

Optimization in Drug Discovery (Methods in Pharmacology and Toxicology)

Publisher: Humana Press
Number Of Pages: 436
Publication Date: 2004-09
Sales Rank: 1194865
ISBN / ASIN: 1588293327
EAN: 9781588293329
Binding: Hardcover
Manufacturer: Humana Press
Studio: Humana Press

Book Description:

A panel of researchers and experts from leading universities and major pharmaceutical companies from all over the world systematically describe cutting-edge experimental protocols for the early in vitro evaluation of new chemical entities (NCE). These readily reproducible assays measure such critical parameters as physicochemical properties, adsorption, plasma freeduan.com binding, metabolism, drug interactions, and toxicity. By uncovering early in the discovery stage the defects that can eliminate candidate drugs from preclinical and clinical development, these techniques can save millions of dollars in time and effort.

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