Orphan G Protein-Coupled Receptors and Novel Neuropeptides

Description

Over the last decade it has been shown that orphan G protein-coupled receptors (GPCRs) can be used as targets to discover novel neuropeptides. A dozen neuropeptides have been identified through this approach. Each of these neuropeptides has opened new doors for our understanding of fundamental physiological or behavioral responses. For example the orexins, MCH and ghrelin carry fundamental roles in regulating food intake while neuropeptide S, neuromedin S, the prokineticins and the orexins are major players in modulating sleep and circadian rhythms.

The chapters of this book review the latest research in the field, most of them are written by the original discoverers of the respective novel neuropeptide. Emphasis is set not only on their discovery but also on their functional significance. Since many of these neuropeptides are part of drug discovery programs, this book impacts academic as well as pharmaceutical research.

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1. Ebooks list page : 2617
2. Orphan G Protein-Coupled Receptors and Novel Neuropeptides (2008)
3. The G Protein-Coupled Receptors Handbook
4. G Protein-Coupled Receptors in Drug Discovery
5. Ligand Design for G Protein-coupled Receptors
6. G Protein-Coupled Receptors in Drug Discovery
7. G Protein-Coupled Receptors in Drug Discovery
8. G Protein-Coupled Receptors: Structure, Function, and Ligand Screening
9. G Protein-Coupled Receptors: Structure, Function, and Ligand Screening
10. Methods in Molecular Biology, vol.552 - G Protein-Coupled Receptors in Drug Discovery
11. G Protein-coupled Receptors: Molecular Pharmacology By Georges Vauquelin, Bengt von Mentzer
12. G Protein-Coupled Receptors as Drug Targets: Analysis of Activation and Constitutive Activity
13. Understanding G Protein-coupled Receptors and their Role in the CNS (The Molecular and Cellular Neurobiology Series)
14. The Serotonin Receptors: From Molecular Pharmacology to Human Therapeutics (The Receptors)
15. The Adrenergic Receptors in the 21st Century (The Receptors)
16. The Adrenergic Receptors in the 21st Century (The Receptors)