PNH and the GPI-Linked Proteins

Description

PNH and the GPI-Linked Proteins

Publisher: Academic Press
Number Of Pages: 296
Publication Date: 2000-02
Sales Rank: 730540
ISBN / ASIN: 0127729402
EAN: 9780127729404
Binding: Hardcover
Manufacturer: Academic Press
Studio: Academic Press
Average Rating: 3

Paroxysmal Nocturnal Hemoglobinuria (PNH) has been recognized for over a century. This mysterious disease is now understood at the level of the gene and the protein. The pathophysiology is related to a class of cell surface proteins with distinctive biochemical and physical characteristics. Recently it has been acknowledged that PNH is not rare, and once sensitive assays--based on the chemistry of the proteins--can be applied to many patients.
Written by international experts in the field, this book includes a number of distinctive characteristics, such as the clinical features of PNH, the mechanism of hemolysis, the biochemistry of glycosylphosphoinositol anchors, and the chemistry and biophysics of GPI-anchored proteins.
This unique and timely volume will have a wide audience, including hematologists and oncologists with a clinical interest in this disease, as well as basic biochemists, immunologists, and cell biologists studying this class of proteins.

Key Features
* Outlines the chemical features of PNH
* Explains the mechanism of hemolysis
* Includes work on the biochemistry of glycophosphoinositol anchors
* Contains descriptions of the chemistry and biophysics of GPI-anchored proteins

http://rapidshare.com/files/45492771/Youn_PNatGPLP.rar

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