Pharmaceutical Biotechnology Second Edition

Description

Pharmaceutical Biotechnology Second Edition
edited by Michael J. Groves


ISBN: 0849318734 |2006 | English
432pages | pdf | size: 14,91 Mb


Pharmaceutical Biotechnology explores the development of protein-based therapeutic substances.
Features:
• Provides a working knowledge of the preparation, stability, and formulation of protein and peptide drugs
• Examines the successful evolution of humanized monoclonal antibodies (MAbs) to treat rheumatoid arthritis and other diseases
• Considers the currently disappointing results of genetic engineering and genomics that have isolated disease-responsible genes without significant clinical effect to date
• Looks at the market and scientific reasons behind the failure of many biotechnology products to live up to their hype
• Discusses regulatory and compendial issues and concludes with a look at future challenges facing biotechnology
Contents
Proteins
Recombinant DNA Basics
Monoclonal Antibodies
Proteomics: A New Emerging Area of Biotechnology
Commonly Used Analytical Techniques for Biotechnology Products
Formulation of Proteins and Peptides
Proteins as Drug Delivery Systems
Proteins and Phospholipids
Pulmonary Drug Delivery Systems for Biomacromolecules
Polymeric Systems for Oral Proten and Peptide Delivery
Vaccines: Ancient Medicines to Modern Therapeutics
Gene Therapy: An Overview of Current Viral and Non-Viral Vectors
Regulatory and Compendial Issues
Some Challenges Relating to the Future of Biopharmaceutical Technology

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