Proteomics

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Description




Title: Proteomics
Description:
Proteomics is an introduction to the exciting new field of proteomics, an interdisciplinary

science that includes biology, bioinformatics, and protein chemistry. The purpose of this book

is to provide the active researcher with an overview of the types of questions being addressed

in proteomics studies and the technologies used to address those questions. Key subjects covered

in this book include: an assessment of the limitations of this approach and outlines new

developments in mass spectrometry that will advance future research high-throughput recombinant

DNA cloning methods used to systematically clone all of the open reading frames of an organism

into plasmid vectors for large scale protein expression and functional studies such as

protein-protein interactions with the two-hybrid system protein structure an overview of

large-scale experimental attempts to determine the three-dimensional structures of

representative sets of proteins computational approaches to determining the three-dimensional

structure of proteins. Proteomics provides a starting point for researchers who would like a

theoretical understanding of the new technologies in the field, and obtain a solid grasp of the

fundamentals before integrating new tools into their experiments. Written with attention to

detail, but without being overwhelmingly technical, Proteomics is a user-friendly guide needed

by most biologists today.

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