Proteomics
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Description
Title: Proteomics
Description:
Proteomics is an introduction to the exciting new field of proteomics, an interdisciplinary
science that includes biology, bioinformatics, and protein chemistry. The purpose of this book
is to provide the active researcher with an overview of the types of questions being addressed
in proteomics studies and the technologies used to address those questions. Key subjects covered
in this book include: an assessment of the limitations of this approach and outlines new
developments in mass spectrometry that will advance future research high-throughput recombinant
DNA cloning methods used to systematically clone all of the open reading frames of an organism
into plasmid vectors for large scale protein expression and functional studies such as
protein-protein interactions with the two-hybrid system protein structure an overview of
large-scale experimental attempts to determine the three-dimensional structures of
representative sets of proteins computational approaches to determining the three-dimensional
structure of proteins. Proteomics provides a starting point for researchers who would like a
theoretical understanding of the new technologies in the field, and obtain a solid grasp of the
fundamentals before integrating new tools into their experiments. Written with attention to
detail, but without being overwhelmingly technical, Proteomics is a user-friendly guide needed
by most biologists today.
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