Structure-based Drug Discovery by Harren Jhoti

Description

Discovering new medicines is becoming more challenging and the pharmaceutical industry is looking to new technologies to help in this mission. Structure-based drug discovery methods have been transformed in the last 5-10 years and are now having a major impact on the discovery of new drugs. Some of the most exciting developments in the field, such as Fragment-based methods, are described in this book.

The book describes the latest developments in technologies that can be used to obtain the 3-D structures including the high profile structural genomics approaches being utilised worldwide. The use of 3-D protein structures in new, Fragment-based, approaches to drug discovery are described in some detail. This book includes experimental approaches using X-ray crystallography and NMR for Fragment-based screening as we as other biophysical methods for studying protein/ligand interactions. In addition, developments in computational chemistry methodology are covered together with an assessment of practical applications.

This book is an invaluable resource for medicinal chemists in industry, computational chemists, drug discovery scientists and postgraduates in chemistry or structural biology.

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1. Ebooks list page : 3613
2. Structure-based Drug Discovery
3. Burger's Medicinal Chemistry and Drug Discovery, Drug Discovery and Drug Development (Volume 2) (ReUp)
4. Analogue-based Drug Discovery
5. Analogue-based Drug Discovery
6. Fragment-based Approaches in Drug Discovery
7. Carbohydrate-based Drug Discovery, 2 Volume Set
8. Structure-Based Drug Design
9. Aminoglycoside Antibiotics: From Chemical Biology to Drug Discovery (Wiley Series in Drug Discovery and Development)
10. Chemogenomics: Knowledge-based Approaches to Drug Discovery
11. Aminoglycoside Antibiotics: From Chemical Biology to Drug Discovery (Wiley Series in Drug Discovery
12. Veerapandian, Structure-Based Drug Design
13. Veerapandian, ?Structure-Based Drug Design?
14. structure-based drug design and pharmacophores
15. Burger's Medicinal Chemistry and Drug Discovery, Drug Discovery (Volume 1) (ReUp)
16. Functional Protein Microarrays in Drug Discovery (Drug Discovery Series)