THE WAR ON CANCER

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THE WAR ON CANCER

Why We're Losing the War on Cancer?and How to Win It Avastin, Erbitux, Gleevec... The new wonder drugs might make you think we're finally beating this dreaded scourge. We're not. Here's how to turn the fight around, in part one of our special investigation into how to win the war on cancer. By Clifton Leaf

It's strange to think that I can still remember the smell after all this time. The year was 1978, not long after my 15th birthday, and I'd sneaked into my brother's bedroom. There, on a wall of shelves that stretched to the ceiling, were the heaviest books we had in our house?24 volumes of the Encyclopedia Britannica. The maroon spines were coated in a film of dust, I remember. The pages smelled as if a musty old pillow had been covered in mint.

I carefully pulled out the volume marked Halicarnassus to Immingham and turned to the entry for Hodgkin's disease. It took forever to read the half-dozen paragraphs, the weighty book spread open on my lap like a Bible. There was talk of a mysterious "lymphatic system," of "granulomas" and "gamma rays," as though this disease?the one the doctor had just told me I had?was something out of science fiction. But the last line I understood all too well: Seventy-five percent of the people who got it would die within five years.

As it turns out, I did not die from Hodgkin's, though the cancer had already spread from my neck to my lungs and spleen. I lost my spleen to surgery and most of my hair to chemotherapy and radiation. But I was lucky enough to get into a clinical trial at the National Cancer Institute that was testing a new combination therapy?four toxic chemicals, together called MOPP, plus those invisible gamma rays, which flowed from an enormous cobalt 60 machine three stories below ground. The nurses who stuck needles in my arm were so kind I fell in love with them. The brilliant doctor who tattooed the borders of an imaginary box on my chest, then zapped me with radiation for four weeks, had warm pudgy hands and a comic look of inspiration, as though he'd thought of something funny just before entering the exam room. The American taxpayer even footed the bill.

Most of all, of course, I was lucky to survive. So it makes the question I am about to ask sound particularly ungrateful: Why have we made so little progress in the War on Cancer?

The question may come as a shock to anyone who has witnessed a loved one survive the dread disease?or marveled at Lance Armstrong powering to his fifth Tour de France victory after beating back testicular cancer, or received a fundraising letter saying that a cure is within our grasp. Most recently........


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