Target Validation in Drug Discovery (2006)

Description

Description: This work presents a comprehensive contemporary framework for approaching target validation in drug discovery. It begins with a detailed description of new enabling technologies, including aptamers, RNA interference, functional genomics, and proteomics. The next section looks at biologic drug development with in-depth discussion of lessons learned from such well-known cases as Erbitux, Herceptin, and Avastin. Additional targets known as "second generation" drugs, which can be identified when disease pathways are validated by biologics, present new possible small molecule therapeutics and serve as the focus of the final section of the book.




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1. Ebooks list page : 1622
2. Target Discovery and Validation Reviews and Protocols, Vol 1: Emerging Strategies for Targets and Biomarker Discovery (Methods
3. In Silico Technologies in Drug Target Identification and Validation
4. Target Discovery and Validation, Volume 2: Reviews and Protocols: Emerging Molecular Targets and Treatment Options (Methods in
5. Burger's Medicinal Chemistry and Drug Discovery, Drug Discovery and Drug Development (Volume 2) (ReUp)
6. Aminoglycoside Antibiotics: From Chemical Biology to Drug Discovery (Wiley Series in Drug Discovery and Development)
7. Aminoglycoside Antibiotics: From Chemical Biology to Drug Discovery (Wiley Series in Drug Discovery
8. Burger's Medicinal Chemistry and Drug Discovery, Drug Discovery (Volume 1) (ReUp)
9. Functional Protein Microarrays in Drug Discovery (Drug Discovery Series)
10. Biochips As Pathways To Drug Discovery (Drug Discovery Series)
11. Drug Transporters: Molecular Characterization and Role in Drug Disposition (Wiley Series in Drug Discovery and Development)
12. Screening: Methods for Experimentation in Industry, Drug Discovery, and Genetics, 1st edition, 2006-02
13. Screening: Methods for Experimentation in Industry, Drug Discovery, and Genetics, 1st edition, 2006-
14. Protein Discovery Technologies (Drug Discovery Series)
15. Protein Discovery Technologies (Drug Discovery Series)
16. Drug Delivery: Principles and Applications (Wiley Series in Drug Discovery and Development)