The G Protein-Coupled Receptors Handbook

Description

A comprehensive survey of the many recent advances in the field of G protein-coupled receptors (GPCR). The authors describe the current knowledge of GPCR receptor structure and function, the different mechanisms involved in the regulation of GPCR function, and the role of pharmacological chaperones in GPCR folding and maturation. They also present new findings about how GPCR dimerization/oligomerization modifies the properties of individual receptors and show how recent developments are leading to significant advances in drug discovery, such as the detection of ligands for orphan GPCRs. Also discussed are the most recent developments that could lead to new drug discoveries: the role of GPCRs in mediating pain, the development of receptor-type selective drugs based on the structural plasticity of receptor activation, and the identification of natural ligands of orphan GPCRs (deorphanization) as possible drug targets.

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1. Ebooks list page : 1603
2. G Protein-Coupled Receptors in Drug Discovery
3. Ligand Design for G Protein-coupled Receptors
4. G Protein-Coupled Receptors in Drug Discovery
5. G Protein-Coupled Receptors in Drug Discovery
6. Orphan G Protein-Coupled Receptors and Novel Neuropeptides
7. Orphan G Protein-Coupled Receptors and Novel Neuropeptides (2008)
8. G Protein-Coupled Receptors: Structure, Function, and Ligand Screening
9. G Protein-Coupled Receptors: Structure, Function, and Ligand Screening
10. Methods in Molecular Biology, vol.552 - G Protein-Coupled Receptors in Drug Discovery
11. G Protein-coupled Receptors: Molecular Pharmacology By Georges Vauquelin, Bengt von Mentzer
12. G Protein-Coupled Receptors as Drug Targets: Analysis of Activation and Constitutive Activity
13. Understanding G Protein-coupled Receptors and their Role in the CNS (The Molecular and Cellular Neurobiology Series)
14. The Serotonin Receptors: From Molecular Pharmacology to Human Therapeutics (The Receptors)
15. Inductively Coupled Plasma Mass Spectrometry Handbook
16. Inductively Coupled Plasma Mass Spectrometry Handbook